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142 J KARDIOL 2008; 15 (5–6)

ÖKG-Jahrestagung – Abstracts

Compliance is very good with regard to attendance, which is cer-

tainly due in part to the excellent networking that already exists in

this ethnic group.

Possible Interaction Between Gender and Cardio-

vascular Risk Factors in First-Second-Generation

Turkish Migrant Women 014

A. Bader, D. Musshauser, A. Chwosta, M. Hochleitner

Women’s Health Centre, Medical University of Innsbruck

In the third year of a CVD prevention program aimed at both sec-

ond- and first-generation Turkish migrant women in rural Austria

910 participants completed a questionnaire on self-assessed CVD

risk factors. Second generation was defined as having gone to

school in Austria. More than half of the participants (477) were

young adult women between 20 und 40 years of age. As expected,

results varied widely between first and second generation.

The greatest differences were found in gender- and lifestyle-related

risk factors. BMI > 30 (first 26.3 %/second 6.2 %), exercise 3 times

a week (36.3 %/71.3 %) and healthy diet (61.7 %/83.6 %) showed

significantly better results among second-generation women.

Smoking (16.7 %/38.5 %) showed significantly worse results in

second-generation women.

Having fewer language barriers, twice as many second- as first-gen-

eration migrants consume German-language media.

Even though fewer language barriers led better awareness of health

risk factors to be expected in second-generation migrants, they were

less informed about their clinically measured risk factors like blood

pressure, cholesterol and blood glucose levels than was the first

migrant generation in the same age group. Thus, culturally coded

gender expectations might be a stronger impetus for health behavior

than health information for second-generation migrant women.

Healthcare providers should strengthen positive health behavior of

the culture of origin and the host culture to support good CVD

health of women whose gender roles are in transition.

Primary Prevention of Coronary Heart Disease in

Women 015

A. Bader, M. Hochleitner

Women’s Health Centre, Medical University of Innsbruck

Heart death is the number-one killer of women in Austria. The

Women’s Health Office thus offered check-ups specially for

women outside the hospital and doctor’s office, namely as stop-ins.

We offered health information material specifically for women and

a 30-min check-up covering blood pressure, BMI, cholesterol,

blood glucose and a doctor’s consultation. For further treatment the

women were referred to their primary-care physician.

In 2003, 304 women (average age 53.3 years ± 16.7 years) partici-

pated. A standardized questionnaire evaluated cardiac risk. Of the

respondents 118 (38.8 %) reported a family history of risk, 234

(79.9 %) sports (minimum three times per week). 274 (90.1 %) re-

ported a healthy diet including fiber, and 43 (14.1 %) smoked. The

check-up also included a questionnaire for self-evaluation of health:

24 (6.6 %) reported not so good and only 4 (1.1 %) poor health; 57

(16.0 %) reported pre-existing cardiocirculatory disorders. An out-

patient women’s health clinic was requested by 238 (78.3 %)

women; 285 (93.8 %) wanted more health information specifically

for women.

Values measured: total cholesterol > 200 in 171 (56.3 %) women,

blood glucose > 126 in 47 (15.5 %), blood pressure > 160/90 in 56

(18.4 %), BMI > 30 in 33 (10.9 %).

Ultimately, the great discrepancy between the risk profile given by

the respondents and the measured values is not surprising. This

shows there is a huge need for information, as reflected in the wish

for an out-patient women’s health clinic providing more specific

health information. Despite Austria’s free access to medical care for

everyone, there remains a need for low-threshold health informa-

tion specifically for women.

The Metabolic Syndrome, Angiographically Deter-

mined Stable Coronary Artery Disease, and Subclini-

cal Inflammation

030

St. Beer, P. Rein, C. H. Saely, A. Vonbank, M. Woess, C. Boehnel, V. Jankovic,

H. Drexel

VIVIT Institute, Feldkirch

Background The metabolic syndrome (MetS) and stable coro-

nary artery disease (CAD) frequently coincide; the individual con-

tributions of these entities to subclinical inflammation have not

been investigated yet.

Objective We therefore aimed at investing markers of inflamma-

tion in patients with the MetS, in patients with CAD, and in patients

who had both, the MetS and CAD.

Methods We enrolled 935 consecutive patients undergoing coro-

nary angiography for the evaluation of suspected or established sta-

ble CAD. The MetS was defined according to National Cholesterol

Education Programme Adult Treatment Panel III criteria; coronary

stenoses with lumen narrowing ≥ 50 % were considered significant.

Results From our patients 520 (55.6 %) had significant coronary

stenoses; the prevalence of the MetS was higher in our patients with

significant stenoses than in those without such lesions (39.0 % vs

32.8 %; p = 0.048). The inflammatory markers hsCRP and white

blood cell count (WBC) were significantly higher in MetS patients

than in those without the MetS both among patients with significant

coronary stenoses (0.49 ± 0.71 vs 0.42 ± 0.88 mg/dl; p = 0.004 and

7.0 ± 1.8 vs 6.5 ± 1.8 G/l; p = 0.003, respectively) and in subjects

who did not have such lesions (0.44 ± 0.51 vs 0.37 ± 0.54 mg/dl;

p = 0.004 and 7.1 ± 1.8 vs 6.4 ± 1.8 G/l; p < 0.001, respectively).

In contrast, these inflammatory markers were not significantly

elevated in patients with significant stenoses among subjects with

the MetS (p = 0.776 and p = 0.713, respectively) nor among those

who did not have the MetS (p = 0.882 and p = 0.119, respectively).

Similar results were obtained with the International Diabetes Federa-

tion definition of the MetS.

Conclusions We conclude that subclinical inflammation is

strongly and significantly associated with the MetS but not with

angiographically determined stable CAD.

BNP in Low-Flow, Low-Gradient Aortic Stenosis is

Strongly Related to Functional Capacity. Results

from the Multicenter TOPAS Study 080

J. Bergler-Klein, G. Mundigler, P. Pibarot, I. Burwash, J. G. Dumesnil, D. Meshkat,

M.-A. Clavel, R. Rosenhek, R. Beanlands, C. Fuchs, H. Baumgartner

Department of Cardiology, Medical University of Vienna, Austria; Laval University,

Sainte Foy, Quebec, Canada; University of Ottawa Heart Institute, Ontario, Canada

Background We have previously reported that plasma levels of

BNP (B-type natriuretic peptide) are a strong predictor of outcome

in low-flow low-gradient aortic stenosis (AS). More recently, we

found impaired functional capacity in the six-minute walk test to be

associated with poor outcome in this challenging subset of patients.

The objective of the present study was to evaluate the relationship

between BNP and parameters of functional capacity in low flow AS.

Methods BNP measurements and dobutamine stress echocardio-

graphy (DSE) were performed in 71 pts with low-flow AS (effective

orifice area [EOA] ≤ 1.2 cm

, indexed EOA ≤ 0.6 cm

, mean

gradient ≤ 40 mmHg, LVEF ≤ 40 %). Functional capacity was as-

sessed using the Duke Activity Status Index (DASI) and six minute

walk test (6MWT) was performed in a subset of 54 pts.

Results Median BNP was 545 (inter-quartile range: 276 to

982) pg/ml. Mean DASI was 26 ± 14 and mean 6MWT distance was

316 ± 122 m. Log BNP was significantly related to DASI (r = –0.31;

p < 0.01) and 6MWT distance (r = –0.56; p < 0.0001; Figure 1), as

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